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Solution conformations and dynamics of substrate-bound cytochrome P450 MycG
MycG is a P450 monoxygenase that catalyzes the sequential hydroxylation and epoxidation of mycinamicin IV (M-IV), the last two steps in the biosynthesis of mycinamicin II, a macrolide antibiotic isolated from M. griseorubida. The crystal structure of MycG with M-IV bound was previously determined, b...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520640/ https://ncbi.nlm.nih.gov/pubmed/28488849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00291 |
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