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Solution conformations and dynamics of substrate-bound cytochrome P450 MycG

MycG is a P450 monoxygenase that catalyzes the sequential hydroxylation and epoxidation of mycinamicin IV (M-IV), the last two steps in the biosynthesis of mycinamicin II, a macrolide antibiotic isolated from M. griseorubida. The crystal structure of MycG with M-IV bound was previously determined, b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochemistry
Egile Nagusiak: Tietz, Drew R., Podust, Larissa M., Sherman, David H., Pochapsky, Thomas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520640/
https://ncbi.nlm.nih.gov/pubmed/28488849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00291
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