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Substrate Recognition by the Multifunctional Cytochrome P450 MycG in Mycinamicin Hydroxylation and Epoxidation Reactions

The majority of characterized cytochrome P450 enzymes in actinomycete secondary metabolic pathways are strictly substrate-, regio-, and stereo-specific. Examples of multifunctional biosynthetic cytochromes P450 with broader substrate and regio-specificity are growing in number and are of particular...

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Détails bibliographiques
Auteurs principaux: Li, Shengying, Tietz, Drew R., Rutaganira, Florentine U., Kells, Petrea M., Anzai, Yojiro, Kato, Fumio, Pochapsky, Thomas C., Sherman, David H., Podust, Larissa M.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488060/
https://ncbi.nlm.nih.gov/pubmed/22952225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410340
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