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Functional Analysis of MycCI and MycG, Cytochrome P450 Enzymes involved in Biosynthesis of Mycinamicin Macrolide Antibiotics

Macrolide antibiotics are a class of valuable anti-infective agents that include a macrolactone ring, at least one appended sugar unit, and in most cases, additional functionalization in the form of hydroxyl and/or epoxide groups. There is a significant body of work to understand assembly of the pol...

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Bibliografiske detaljer
Main Authors: Anzai, Yojiro, Li, Shengying, Chaulagain, Mani Raj, Kinoshita, Kenji, Kato, Fumio, Montgomery, John, Sherman, David H.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774819/
https://ncbi.nlm.nih.gov/pubmed/18804032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.07.014
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