Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

The Tie receptors with their Angiopoietin ligands act as regulators of angiogenesis and vessel maturation. Tie2 exerts its functions through its supposed endothelial-specific expression. Yet, Tie2 is also expressed at lower levels by pericytes and it has not been unravelled through which mechanisms...

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Udgivet i:Nat Commun
Main Authors: Teichert, Martin, Milde, Laura, Holm, Annegret, Stanicek, Laura, Gengenbacher, Nicolas, Savant, Soniya, Ruckdeschel, Tina, Hasanov, Zulfiyya, Srivastava, Kshitij, Hu, Junhao, Hertel, Stella, Bartol, Arne, Schlereth, Katharina, Augustin, Hellmut G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520106/
https://ncbi.nlm.nih.gov/pubmed/28719590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16106
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