Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs

Lipopolysaccharide (LPS) contributes to asthma exacerbations and development of inhaled corticosteroid insensitivity. Complete resistance to systemic corticosteroids is rare, and most patients lie on a continuum of steroid responsiveness. This study aimed to examine the sensitivity of combined ovalb...

Full description

Saved in:
Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Lowe, Alexander P. P., Thomas, Rhian S., Nials, Anthony T., Kidd, Emma J., Broadley, Kenneth J., Ford, William R.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2017
Subjects:
Inflammation, Immunopharmacology, and Asthma
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520105/
https://ncbi.nlm.nih.gov/pubmed/28576975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241927
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items