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Adjustment of sensitisation and challenge protocols restores functional and inflammatory responses to ovalbumin in guinea-pigs

INTRODUCTION: Inhalation of antigen in atopic asthma induces early (EAR) and late asthmatic responses (LARs), inflammatory cell infiltration and airways hyperresponsiveness (AHR). Previously, we have established a protocol of sensitisation and subsequent ovalbumin (Ova) inhalation challenge in guine...

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Pubblicato in:J Pharmacol Toxicol Methods
Autori principali: Lowe, Alexander P.P., Broadley, Kenneth J., Nials, Anthony T., Ford, William R., Kidd, Emma J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370377/
https://ncbi.nlm.nih.gov/pubmed/25450500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vascn.2014.10.007
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