Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs

Lipopolysaccharide (LPS) contributes to asthma exacerbations and development of inhaled corticosteroid insensitivity. Complete resistance to systemic corticosteroids is rare, and most patients lie on a continuum of steroid responsiveness. This study aimed to examine the sensitivity of combined ovalb...

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Bibliografische gegevens
Gepubliceerd in:J Pharmacol Exp Ther
Hoofdauteurs: Lowe, Alexander P. P., Thomas, Rhian S., Nials, Anthony T., Kidd, Emma J., Broadley, Kenneth J., Ford, William R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2017
Onderwerpen:
Inflammation, Immunopharmacology, and Asthma
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520105/
https://ncbi.nlm.nih.gov/pubmed/28576975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241927
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