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Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs

Lipopolysaccharide (LPS) contributes to asthma exacerbations and development of inhaled corticosteroid insensitivity. Complete resistance to systemic corticosteroids is rare, and most patients lie on a continuum of steroid responsiveness. This study aimed to examine the sensitivity of combined ovalb...

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Bibliografiske detaljer
Udgivet i:J Pharmacol Exp Ther
Main Authors: Lowe, Alexander P. P., Thomas, Rhian S., Nials, Anthony T., Kidd, Emma J., Broadley, Kenneth J., Ford, William R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520105/
https://ncbi.nlm.nih.gov/pubmed/28576975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241927
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