Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

A functioning gene drive system could fundamentally change our strategies for the control of vector-borne diseases by facilitating rapid dissemination of transgenes that prevent pathogen transmission or reduce vector capacity. CRISPR/Cas9 gene drive promises such a mechanism, which works by converti...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Champer, Jackson, Reeves, Riona, Oh, Suh Yeon, Liu, Chen, Liu, Jingxian, Clark, Andrew G., Messer, Philipp W.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518997/
https://ncbi.nlm.nih.gov/pubmed/28727785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006796
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы