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Evolution of Resistance Against CRISPR/Cas9 Gene Drive

CRISPR/Cas9 gene drive (CGD) promises to be a highly adaptable approach for spreading genetically engineered alleles throughout a species, even if those alleles impair reproductive success. CGD has been shown to be effective in laboratory crosses of insects, yet it remains unclear to what extent pot...

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Pubblicato in:Genetics
Autori principali: Unckless, Robert L., Clark, Andrew G., Messer, Philipp W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289854/
https://ncbi.nlm.nih.gov/pubmed/27941126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.197285
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