Wird geladen...
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.
Point mutations in the p53 gene are the most frequently identified genetic change in human cancer. They convert murine p53 from a tumour suppressor gene into a dominant transforming oncogene able to immortalize primary cells and bring about full transformation in combination with an activated ras ge...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
1990
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1691710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08279.x |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|