טוען...
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.
Point mutations in the p53 gene are the most frequently identified genetic change in human cancer. They convert murine p53 from a tumour suppressor gene into a dominant transforming oncogene able to immortalize primary cells and bring about full transformation in combination with an activated ras ge...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
1990
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC551855/ https://ncbi.nlm.nih.gov/pubmed/1691710 |
| תגים: |
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