Interactions between Human Glutamate Carboxypeptidase II and Urea-Based Inhibitors: Structural Characterization()

Urea-based, low molecular weight ligands of glutamate carboxypeptidase II (GCPII) have demonstrated efficacy in various models of neurological disorders and can serve as imaging agents for prostate cancer. To enhance further development of such compounds, we determined X-ray structures of four compl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Barinka, Cyril, Byun, Youngjoo, Dusich, Crystal L., Banerjee, Sangeeta R., Chen, Ying, Castanares, Mark, Kozikowski, Alan P., Mease, Ronnie C., Pomper, Martin G., Lubkowski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516903/
https://ncbi.nlm.nih.gov/pubmed/19053759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800765e
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados