Bolstering the Number and Function of HSV-1-Specific CD8(+) T(EM) and T(RM) cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease

Herpes simplex virus type 1 (HSV-1) is a prevalent human pathogen that infects over 3.72 billion individuals worldwide and can cause potentially blinding recurrent corneal herpetic disease. HSV-1 establishes latency within sensory neurons of trigeminal ganglia (TG) and TG-resident CD8(+) T cells pla...

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Publicado no:J Immunol
Main Authors: Khan, Arif A., Srivastava, Ruchi, Chentoufi, Aziz A., Kritzer, Elizabeth, Chilukuri, Sravya, Garg, Sumit, Yu, David C., Vahed, Hawa, Huang, Lei, Syed, Sabrina A., Furness, Julie N., Tran, Tien T, Anthony, Nesburn B., McLaren, Christine E., Sidney, John, Sette, Alessandro, Noelle, Randolph J., BenMohamed, Lbachir
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515716/
https://ncbi.nlm.nih.gov/pubmed/28539429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700145
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