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The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8(+) T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits
Persistent pathogens, such as herpes simplex virus 1 (HSV-1), have evolved a variety of immune evasion strategies to avoid being detected and destroyed by the host's immune system. A dynamic cross talk appears to occur between the HSV-1 latency-associated transcript (LAT), the only viral gene t...
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| Udgivet i: | J Virol |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810530/ https://ncbi.nlm.nih.gov/pubmed/26842468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02450-15 |
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