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The Herpes Simplex Virus Type 1 Latency-Associated Transcript Inhibits Phenotypic and Functional Maturation of Dendritic Cells

We recently found that the herpes simplex virus-1 (HSV-1) latency-associated transcript (LAT) results in exhaustion of virus-specific CD8(+) T cells in latently-infected trigeminal ganglia (TG). In this study we sought to determine if this impairment may involve LAT directly and/or indirectly interf...

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Detalhes bibliográficos
Main Authors: Chentoufi, Aziz Alami, Dervillez, Xavier, Dasgupta, Gargi, Nguyen, Chelsea, Kabbara, Khaled W., Jiang, Xianzhi, Nesburn, Anthony B., Wechsler, Steven L., BenMohamed, Lbachir
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366336/
https://ncbi.nlm.nih.gov/pubmed/22512280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2011.0091
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