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The Locus Encompassing the Latency-Associated Transcript of Herpes Simplex Virus Type 1 Interferes with and Delays Interferon Expression in Productively Infected Neuroblastoma Cells and Trigeminal Ganglia of Acutely Infected Mice

The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) is the only abundant viral transcript expressed in latently infected neurons. LAT inhibits apoptosis, suggesting that it regulates latency by promoting the survival of infected neurons. The LAT locus also contains a newly de...

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Bibliografiske detaljer
Main Authors: Peng, Weiping, Henderson, Gail, Inman, Melissa, BenMohamed, Lbachir, Perng, Guey-Chuen, Wechsler, Steven L., Jones, Clinton
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091686/
https://ncbi.nlm.nih.gov/pubmed/15858001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6162-6171.2005
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