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Massively parallel sequencing analysis of synchronous fibroepithelial lesions supports the concept of progression from fibroadenoma to phyllodes tumor

Phyllodes tumors (PTs) and fibroadenomas (FAs) are fibroepithelial lesions (FELs) of the breast. Although mutations affecting exon 2 of MED12 are highly recurrent in FAs and PTs, TERT promoter hotspot mutations are frequently found in PTs but are vanishingly rare in FAs. Malignant transformation of...

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Bibliografski detalji
Izdano u:NPJ Breast Cancer
Glavni autori: Piscuoglio, Salvatore, Geyer, Felipe C, Burke, Kathleen A, Murray, Melissa P, Ng, Charlotte KY, Mota, Alba, Marchio, Caterina, Berman, Samuel H, Norton, Larry, Brogi, Edi, Weigelt, Britta, Reis-Filho, Jorge S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515337/
https://ncbi.nlm.nih.gov/pubmed/28721388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbcancer.2016.35
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