Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression

Phyllodes tumours (PTs) are breast fibroepithelial lesions that are graded based on histological criteria as benign, borderline or malignant. PTs may recur locally. Borderline PTs and malignant PTs may metastasize to distant sites. Breast fibroepithelial lesions, including PTs and fibroadenomas, are...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Piscuoglio, Salvatore, Ng, Charlotte K Y, Murray, Melissa, Burke, Kathleen A, Edelweiss, Marcia, Geyer, Felipe C, Macedo, Gabriel S, Inagaki, Akiko, Papanastasiou, Anastasios D, Martelotto, Luciano G, Marchio, Caterina, Lim, Raymond S, Ioris, Rafael A, Nahar, Pooja K, De Bruijn, Ino, Smyth, Lillian, Akram, Muzaffar, Ross, Dara, Petrini, John H, Norton, Larry, Solit, David B, Baselga, Jose, Brogi, Edi, Ladanyi, Marc, Weigelt, Britta, Reis-Filho, Jorge S
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962788/
https://ncbi.nlm.nih.gov/pubmed/26832993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4672
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