Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways

Breast fibroepithelial lesions (fibroadenomas and phyllodes tumors) are underpinned by recurrent MED12 exon 2 mutations, which are more common in fibroadenomas and benign phyllodes tumors. TERT promoter hotspot mutations have been documented in phyllodes tumors, and found to be more frequent in bord...

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Vydáno v:NPJ Breast Cancer
Hlavní autoři: Pareja, Fresia, Geyer, Felipe C., Kumar, Rahul, Selenica, Pier, Piscuoglio, Salvatore, Ng, Charlotte K. Y., Burke, Kathleen A., Edelweiss, Marcia, Murray, Melissa P., Brogi, Edi, Weigelt, Britta, Reis-Filho, Jorge S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638820/
https://ncbi.nlm.nih.gov/pubmed/29043292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-017-0042-6
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