Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways

Breast fibroepithelial lesions (fibroadenomas and phyllodes tumors) are underpinned by recurrent MED12 exon 2 mutations, which are more common in fibroadenomas and benign phyllodes tumors. TERT promoter hotspot mutations have been documented in phyllodes tumors, and found to be more frequent in bord...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:NPJ Breast Cancer
Auteurs principaux: Pareja, Fresia, Geyer, Felipe C., Kumar, Rahul, Selenica, Pier, Piscuoglio, Salvatore, Ng, Charlotte K. Y., Burke, Kathleen A., Edelweiss, Marcia, Murray, Melissa P., Brogi, Edi, Weigelt, Britta, Reis-Filho, Jorge S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638820/
https://ncbi.nlm.nih.gov/pubmed/29043292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-017-0042-6
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires