Nuclear Proximity of Mtr4 with RNA exosome restricts DNA mutational asymmetry

The distribution of sense and antisense strand DNA mutations on transcribed duplex DNA contributes to the development of immune and neural systems along with the progression of cancer. Because developmentally matured B cells undergo biologically programmed strand-specific DNA mutagenesis at focal DN...

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Pubblicato in:Cell
Autori principali: Lim, Junghyun, Giri, Pankaj Kumar, Kazadi, David, Laffleur, Brice, Zhang, Wanwei, Grinstein, Veronika, Pefanis, Evangelos, Brown, Lewis M., Ladewig, Erik, Martin, Ophélie, Chen, Yuling, Rabadan, Raul, Boyer, François, Rothschild, Gerson, Cogné, Michel, Pinaud, Eric, Deng, Haiteng, Basu, Uttiya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515252/
https://ncbi.nlm.nih.gov/pubmed/28431250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.03.043
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