Noncoding RNA transcription targets AID to divergently transcribed loci in B cells

The vast majority of the mammalian genome has the potential to expressnoncoding RNA (ncRNA). The 11-subunit RNA exosome complex is the main source of cellular 3′–5′ exoribonucleolytic activity and potentially regulates the mammalian noncoding transcriptome(1). Here we generated a mouse model in whic...

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發表在:Nature
Main Authors: Pefanis, Evangelos, Wang, Jiguang, Rothschild, Gerson, Lim, Junghyun, Chao, Jaime, Rabadan, Raul, Economides, Aris N., Basu, Uttiya
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372240/
https://ncbi.nlm.nih.gov/pubmed/25119026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13580
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