Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells

Noncoding RNAs are exquisitely titrated by the cellular RNA surveillance machinery for regulating diverse biological processes. The RNA exosome, the predominant 3′ RNA exoribonuclease in mammalian cells, is composed of nine core and two catalytic subunits. Here, we developed a mouse model with a con...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Laffleur, Brice, Lim, Junghyun, Zhang, Wanwei, Chen, Yiyun, Pefanis, Evangelos, Bizarro, Jonathan, Batista, Carolina R., Wu, Lijing, Economides, Aris N., Wang, Jiguang, Basu, Uttiya
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011275/
https://ncbi.nlm.nih.gov/pubmed/33526923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-00772-0
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