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RNA exosome and Non-coding RNA coupled mechanisms in AID mediated genomic alterations

The eukaryotic RNA exosome is a well-conserved protein complex with ribonuclease activity implicated in RNA metabolism. Various families of non-coding RNAs (ncRNAs) have been identified as substrates of the complex, underscoring its role as a ncRNA processing/degradation unit. However, the role of R...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Laffleur, Brice, Basu, Uttiya, Lim, Junghyun
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500447/
https://ncbi.nlm.nih.gov/pubmed/28069372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.12.021
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