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Local alignment of ligand binding sites in proteins for polypharmacology and drug repositioning

The administration of drugs is a key strategy in pharmacotherapy to treat diseases. Drugs are typically developed to modulate the function of specific proteins, which are directly associated with particular disease states. Nonetheless, recent studies suggest that protein-drug interactions are rather...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Autor principal: Brylinski, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513668/
https://ncbi.nlm.nih.gov/pubmed/28451975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7015-5_9
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