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eMatchSite: Sequence Order-Independent Structure Alignments of Ligand Binding Pockets in Protein Models

Detecting similarities between ligand binding sites in the absence of global homology between target proteins has been recognized as one of the critical components of modern drug discovery. Local binding site alignments can be constructed using sequence order-independent techniques, however, to achi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Brylinski, Michal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168975/
https://ncbi.nlm.nih.gov/pubmed/25232727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003829
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