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Protein Functional Surfaces: Global Shape Matching and Local Spatial Alignments of Ligand Binding Sites

BACKGROUND: Protein surfaces comprise only a fraction of the total residues but are the most conserved functional features of proteins. Surfaces performing identical functions are found in proteins absent of any sequence or fold similarity. While biochemical activity can be attributed to a few key r...

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Detalhes bibliográficos
Main Authors: Binkowski, T Andrew, Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626596/
https://ncbi.nlm.nih.gov/pubmed/18954462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-45
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