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Protein Functional Surfaces: Global Shape Matching and Local Spatial Alignments of Ligand Binding Sites
BACKGROUND: Protein surfaces comprise only a fraction of the total residues but are the most conserved functional features of proteins. Surfaces performing identical functions are found in proteins absent of any sequence or fold similarity. While biochemical activity can be attributed to a few key r...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626596/ https://ncbi.nlm.nih.gov/pubmed/18954462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-45 |
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