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Recognizing protein-ligand binding sites by global structural alignment and local geometry refinement

Proteins perform functions through interacting with other molecules. However, structural details for most of the protein-ligand interactions are unknown. We present a new comparative approach (COFACTOR) to recognize functional sites of protein-ligand interactions using low-resolution protein structu...

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Detalhes bibliográficos
Main Authors: Roy, Ambrish, Zhang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372652/
https://ncbi.nlm.nih.gov/pubmed/22560732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.009
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