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Predicting and characterizing protein functions through matching geometric and evolutionary patterns of protein binding surfaces

Predicting protein functions from structures is an important and challenging task. Although proteins are often thought to be packed as tightly as solids, closer examination based on geometric computation reveals that they contain numerous voids and pockets. Most of them are of random nature, but som...

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Detalhes bibliográficos
Main Authors: Liang, Jie, Tseng, Yan-Yuan, Dundas, Joseph, Binkowski, Andrew, Joachimiak, Andrzej, Ouyang, Zheng, Adamian, Larisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882714/
https://ncbi.nlm.nih.gov/pubmed/20731991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0065-3233(07)75004-0
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