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Predicting protein function and binding profile via matching of local evolutionary and geometric surface patterns

Inferring protein functions from structures is a challenging task, as a large number of orphan protein structures from structural genomics project are now solved without their biochemical functions characterized. For proteins binding to similar substrates or ligands and carrying out similar function...

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Detalhes bibliográficos
Main Authors: Tseng, Yan Yuan, Dundas, Joseph, Liang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670802/
https://ncbi.nlm.nih.gov/pubmed/19154742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.12.072
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