Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats

OBJECTIVE: We evaluated the therapeutic effectiveness of a new, orally active epoxyeicosatrienoic acid analog (EET-A) in rats with angiotensin II (ANG II)-dependent malignant hypertension. METHODS: Malignant hypertension was induced in Cyp1a1-Ren-2 transgenic rats by activation of the renin gene usi...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Hypertens
Glavni autori: Jíchová, Šárka, Kopkan, Libor, Husková, Zuzana, Doleželová, Šárka, Neckář, Jan, Kujal, Petr, Vernerová, Zdenka, Kramer, Herbert J., Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Reddy, Rami N., Falck, John R., Imig, John D., Červenka, Luděk
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510029/
https://ncbi.nlm.nih.gov/pubmed/27428043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001029
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items