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Leishmania donovani restricts mitochondrial dynamics to enhance miRNP stability and target RNA repression in host macrophages

MicroRNAs (miRNAs), the tiny regulatory RNAs, form complexes with Argonaute (Ago) proteins and inhibit gene expression in metazoan cells. While studying parasite-invaded macrophages, we identify a unique mode of gene regulation in which the parasite Leishmania donovani (Ld) causes mitochondrial depo...

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Publicado en:Mol Biol Cell
Autores principales: Chakrabarty, Yogaditya, Bhattacharyya, Suvendra N.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509422/
https://ncbi.nlm.nih.gov/pubmed/28539410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0388
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