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Leishmania donovani restricts mitochondrial dynamics to enhance miRNP stability and target RNA repression in host macrophages
MicroRNAs (miRNAs), the tiny regulatory RNAs, form complexes with Argonaute (Ago) proteins and inhibit gene expression in metazoan cells. While studying parasite-invaded macrophages, we identify a unique mode of gene regulation in which the parasite Leishmania donovani (Ld) causes mitochondrial depo...
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| Veröffentlicht in: | Mol Biol Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509422/ https://ncbi.nlm.nih.gov/pubmed/28539410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0388 |
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