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Leishmania donovani Targets Dicer1 to Downregulate miR-122, Lower Serum Cholesterol, and Facilitate Murine Liver Infection

Leishmania donovani causes visceral leishmaniasis (VL) where the parasite infects and resides inside liver and spleen tissue macrophages. Given the abnormal lipid profile observed in VL patients, we examined the status of serum lipids in an experimental murine model of VL. The murine VL liver displa...

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Autors principals: Ghosh, June, Bose, Mainak, Roy, Syamal, Bhattacharyya, Suvendra N.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605572/
https://ncbi.nlm.nih.gov/pubmed/23498953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.02.005
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