Hyperlipidemia offers protection against Leishmania donovani infection: role of membrane cholesterol

Leishmania donovani (LD), the causative agent of visceral leishmaniasis (VL), extracts membrane cholesterol from macrophages and disrupts lipid rafts, leading to their inability to stimulate T cells. Restoration of membrane cholesterol by liposomal delivery corrects the above defects and offers prot...

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Bibliographische Detailangaben
Hauptverfasser: Ghosh, June, Das, Shantanabha, Guha, Rajan, Ghosh, Debopam, Naskar, Kshudiram, Das, Anjan, Roy, Syamal
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494257/
https://ncbi.nlm.nih.gov/pubmed/23060454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026914
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