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Antimony Resistant Leishmania donovani but Not Sensitive Ones Drives Greater Frequency of Potent T-Regulatory Cells upon Interaction with Human PBMCs: Role of IL-10 and TGF-β in Early Immune Response

In India the sand fly, Phlebotomus argentipes, transmitted parasitic disease termed kala-azar is caused by Leishmania donovani (LD) in humans. These immune-evading parasites have increasingly developed resistance to the drug sodium antimony gluconate in endemic regions. Lack of early diagnosis metho...

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Autors principals: Guha, Rajan, Das, Shantanabha, Ghosh, June, Sundar, Shyam, Dujardin, Jean Claude, Roy, Syamal
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102415/
https://ncbi.nlm.nih.gov/pubmed/25032977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002995
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