Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1

The molecular mechanism of antimony-resistant Leishmania donovani (Sb(R)LD)–driven up-regulation of IL-10 and multidrug-resistant protein 1 (MDR1) in infected macrophages (Mϕs) has been investigated. This study showed that both promastigote and amastigote forms of Sb(R)LD, but not the antimony-sensi...

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Detalhes bibliográficos
Main Authors: Mukherjee, Budhaditya, Mukhopadhyay, Rupkatha, Bannerjee, Bijoylaxmi, Chowdhury, Sayan, Mukherjee, Sandip, Naskar, Kshudiram, Allam, Uday Sankar, Chakravortty, Dipshikha, Sundar, Shyam, Dujardin, Jean-Claude, Roy, Syamal
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574914/
https://ncbi.nlm.nih.gov/pubmed/23341611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213839110
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