A transient reversal of miRNA-mediated repression controls macrophage activation

In mammalian macrophages, the expression of a number of cytokines is regulated by miRNAs. Upon macrophage activation, proinflammatory cytokine mRNAs are translated, although the expression of miRNAs targeting these mRNAs remains largely unaltered. We show that there is a transient reversal of miRNA-...

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Detalhes bibliográficos
Main Authors: Mazumder, Anup, Bose, Mainak, Chakraborty, Abhijit, Chakrabarti, Saikat, Bhattacharyya, Suvendra N
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851954/
https://ncbi.nlm.nih.gov/pubmed/24030283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.149
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