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Spatiotemporal Uncoupling of MicroRNA-Mediated Translational Repression and Target RNA Degradation Controls MicroRNP Recycling in Mammalian Cells

MicroRNA (miRNA)-mediated repression controls expression of more than half of protein-coding genes in metazoan animals. Translation repression is associated with target mRNA degradation initiated by decapping and deadenylation of the repressed mRNAs. Earlier evidence suggests the endoplasmic reticul...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Bose, Mainak, Barman, Bahnisikha, Goswami, Avijit, Bhattacharyya, Suvendra N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288578/
https://ncbi.nlm.nih.gov/pubmed/27895152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00464-16
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