A transient reversal of miRNA-mediated repression controls macrophage activation

In mammalian macrophages, the expression of a number of cytokines is regulated by miRNAs. Upon macrophage activation, proinflammatory cytokine mRNAs are translated, although the expression of miRNAs targeting these mRNAs remains largely unaltered. We show that there is a transient reversal of miRNA-...

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Bibliografiske detaljer
Main Authors: Mazumder, Anup, Bose, Mainak, Chakraborty, Abhijit, Chakrabarti, Saikat, Bhattacharyya, Suvendra N
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851954/
https://ncbi.nlm.nih.gov/pubmed/24030283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.149
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