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HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA
The microRNA (miRNA)-mediated repression of protein synthesis in mammalian cells is a reversible process. Target mRNAs with regulatory AU-rich elements (AREs) in their 3′-untranslated regions (3′-UTR) can be relieved of miRNA repression under cellular stress in a process involving the embryonic leth...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367187/ https://ncbi.nlm.nih.gov/pubmed/22362743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks148 |
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