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Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes

MicroRNAs, a group of small, noncoding RNAs that post-transcriptionally regulate gene expression, play important roles in chondrocyte function and in the development of osteoarthritis. We characterized the dynamic repertoire of the chondrocyte miRNome and miRISC-associated miRNome by deep sequencing...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haseeb, Abdul, Makki, Mohammad Shahidul, Khan, Nazir M., Ahmad, Imran, Haqqi, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680238/
https://ncbi.nlm.nih.gov/pubmed/29123165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15388-4
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