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isomiR-SEA: an RNA-Seq analysis tool for miRNAs/isomiRs expression level profiling and miRNA-mRNA interaction sites evaluation

BACKGROUND: Massive parallel sequencing of transcriptomes, revealed the presence of many miRNAs and miRNAs variants named isomiRs with a potential role in several cellular processes through their interaction with a target mRNA. Many methods and tools have been recently devised to detect and quantify...

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Publicat a:BMC Bioinformatics
Autors principals: Urgese, Gianvito, Paciello, Giulia, Acquaviva, Andrea, Ficarra, Elisa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815201/
https://ncbi.nlm.nih.gov/pubmed/27036505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0958-0
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