Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API

MOTIVATION: MicroRNAs (miRNAs) are small RNA molecules (∼22 nucleotide long) involved in post-transcriptional gene regulation. Advances in high-throughput sequencing technologies led to the discovery of isomiRs, which are miRNA sequence variants. While many miRNA-seq analysis tools exist, the divers...

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Publicat a:Bioinformatics
Autors principals: Desvignes, Thomas, Loher, Phillipe, Eilbeck, Karen, Ma, Jeffery, Urgese, Gianvito, Fromm, Bastian, Sydes, Jason, Aparicio-Puerta, Ernesto, Barrera, Victor, Espín, Roderic, Thibord, Florian, Bofill-De Ros, Xavier, Londin, Eric, Telonis, Aristeidis G, Ficarra, Elisa, Friedländer, Marc R, Postlethwait, John H, Rigoutsos, Isidore, Hackenberg, Michael, Vlachos, Ioannis S, Halushka, Marc K, Pantano, Lorena
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566869/
https://ncbi.nlm.nih.gov/pubmed/31504201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz675
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