Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types

Isoforms of human miRNAs (isomiRs) are constitutively expressed with tissue- and disease-subtype-dependencies. We studied 10 271 tumor datasets from The Cancer Genome Atlas (TCGA) to evaluate whether isomiRs can distinguish amongst 32 TCGA cancers. Unlike previous approaches, we built a classifier t...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Telonis, Aristeidis G., Magee, Rogan, Loher, Phillipe, Chervoneva, Inna, Londin, Eric, Rigoutsos, Isidore
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Computational Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389567/
https://ncbi.nlm.nih.gov/pubmed/28206648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx082
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items