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Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway
In Drosophila, miRNA is processed by Dicer-1 (DCR-1) from its precursor and loaded onto Argonaute1 (AGO1). AGO1 recognizes target mRNAs based on the miRNA sequence and suppresses the expression at post-transcriptional levels. GW182, a P-body component, localizes the AGO1 complex to processing bodies...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704077/ https://ncbi.nlm.nih.gov/pubmed/19451544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1541209 |
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