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Slicer function of Drosophila Argonautes and its involvement in RISC formation

Argonaute proteins play important yet distinct roles in RNA silencing. Human Argonaute2 (hAgo2) was shown to be responsible for target RNA cleavage (“Slicer”) activity in RNA interference (RNAi), whereas other Argonaute subfamily members do not exhibit the Slicer activity in humans. In Drosophila, A...

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Bibliografiska uppgifter
Huvudupphovsmän: Miyoshi, Keita, Tsukumo, Hiroko, Nagami, Tomoko, Siomi, Haruhiko, Siomi, Mikiko C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315391/
https://ncbi.nlm.nih.gov/pubmed/16287716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1370605
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