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Slicer function of Drosophila Argonautes and its involvement in RISC formation
Argonaute proteins play important yet distinct roles in RNA silencing. Human Argonaute2 (hAgo2) was shown to be responsible for target RNA cleavage (“Slicer”) activity in RNA interference (RNAi), whereas other Argonaute subfamily members do not exhibit the Slicer activity in humans. In Drosophila, A...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315391/ https://ncbi.nlm.nih.gov/pubmed/16287716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1370605 |
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