DmGTSF1 is necessary for Piwi–piRISC-mediated transcriptional transposon silencing in the Drosophila ovary

The Piwi–piRNA (PIWI-interacting RNA) complex (Piwi–piRISC) in Drosophila ovarian somatic cells represses transposons transcriptionally to maintain genome integrity; however, the underlying mechanisms remain obscure. Here, we reveal that DmGTSF1, a Drosophila homolog of gametocyte-specific factor 1...

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Detalhes bibliográficos
Main Authors: Ohtani, Hitoshi, Iwasaki, Yuka W., Shibuya, Aoi, Siomi, Haruhiko, Siomi, Mikiko C., Saito, Kuniaki
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744724/
https://ncbi.nlm.nih.gov/pubmed/23913921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.221515.113
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